This paper reports a methodological pivot from the Open Khipu Repository to the Khipu Field Guide (KFG) database, prompted by stalled progress on the OKR, and a full re-analysis of the resulting 650-khipu sample. Three findings recur across every analysis attempted. First, khipu size confounds nearly every derived structural count, explaining 42-70% of its variance; all subsequent models control for it. Second, the two-letter name prefix (AS, UR, HP, QU, JC, MM, KH) identifies the original cataloger, not a site or period, which turns documentation completeness into a second confound that must be modeled explicitly. Controlling for both, khipus cataloged by Hugo Pereyra's Proyecto Quipu (HP) show significantly fewer Ascher sum-relation types than Gary Urton's (UR) khipus (p = 0.044), while the Ascher-cataloged (AS) khipus are too collinear with their own near-total lack of side/direction documentation to assess (VIF = 5.0). Third, generic structural clustering (UMAP+HDBSCAN) does not separate the pooled 650-khipu sample from two independent null models (permutation and Gaussian), corroborating an independent conclusion already reached by the KFG itself; the same test restricted to a single cataloger (UR) proved not reproducible across runtime environments and is reported here as a methodological caveat rather than evidence of structure. A targeted replication of the KFG's own S/Z-knot spatial-block heuristic for calendar/astronomical khipus recovers 8 of 10 published candidates and proposes 34 additional ones under the same criterion.